Alpha BRAIN is likely one of the world’s most talked-about and popular nootropics, and manufacturer Onnit has made it the flagship of their “earth grown” supplements line. TruBrain is more of a newcomer to the space, and the compay, with real neuroscientists on staff, is specializing pretty much only in brain-boosters. While we’ve given great reviews to Alpha BRAIN (read our full review) and truBrain’s liquid shots (read our full review), there are some key differences between the two stacks.

truBrain vs Alpha BRAIN compared. These two powerful nootropic stacks compared, researched, and contrasted to show you which one is best.
Despite sharing some ingredients, l-theanine, tyrosine, and choline-based compounds, truBrain’s shots and Alpha BRAIN are aiming to boost brainpower through different mechanisms. TruBrain’s standard and Boost formulations contain the popular caffeine/l-theanine combo for smoother energy (though they do have a caffeine-free version), whereas Alpha BRAIN is a caffeine-free stack. TruBrain’s signature ingredient is oxiracetam, a powerful compound in the racetam group of compounds. While not as fast-acting as noopept, oxiracetam gave our testers a sustained, quickly-noticeable sharpness to their thoughts, focus, and memory recall.


Overall, truBrain acts a bit faster and feels more immediately potent. Alpha BRAIN‘s effects feel (at least to our testers, individual experiences may vary) more gradual and sustained, a fairly gentle, dependable mental boost that lasts pretty much the whole day.



